Tamoxifen citrate

Tamoxifen citrate API

Tamoxifen is known to have a dual mechanism of action: (1) to compete with 17β-estradiol (E2) at the receptor site and to block the promotional role of E2 in breast cancer; and (2) to bind DNA after metabolic activation and to initiate carcinogenesis.

Tamoxifen citrate API

Cas No :

54965-24-1

Name :

Tamoxifen citrate

Synonyms :

2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid

Molecular Formula :

C32H37NO8

Melting Point :

142 °C

Boiling Point :

N/A

Molecular Weight :

563.6 g/mol

Density :

N/A

Solubility :

The solubility in water is 0.3 mg/L at 20°C; the pH is approx. 3.0-3.5 at 20°C. 5 TC is soluble at 0.2 mg/ml in 0.02 N HCl, at 37°C

Uses :


  • A drug used to treat certain types of breast cancer in women and men, to prevent invasive breast cancer in women who have had ductal carcinoma in situ (abnormal cells in the ducts of the breast), and to prevent breast cancer in women who are at a high risk of developing the disease.