Tamoxifen is known to have a dual mechanism of action: (1) to compete with 17β-estradiol (E2) at the receptor site and to block the promotional role of E2 in breast cancer; and (2) to bind DNA after metabolic activation and to initiate carcinogenesis.
Cas No : | 54965-24-1 |
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Name : | Tamoxifen citrate |
Synonyms : | 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid |
Molecular Formula : | C32H37NO8 |
Melting Point : | 142 °C |
Boiling Point : | N/A |
Molecular Weight : | 563.6 g/mol |
Density : | N/A |
Solubility : | The solubility in water is 0.3 mg/L at 20°C; the pH is approx. 3.0-3.5 at 20°C. 5 TC is soluble at 0.2 mg/ml in 0.02 N HCl, at 37°C |
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