Simvastatin is a statins type of lipid lowering drug and is a synthetic derivative of Aspergillus tumefaciens fermentation products, which is used to control the cholesterol content in blood and prevent cardiovascular disease. Simvastatin is a reductase inhibitor of HMG CoA, which inhibits the synthesis of endogenous derived cholesterol, and is a lipid regulator. It can reduce the cholesterol (TC) content in serum, liver and aorta of hyperlipidemia rabbits, and the level of VLDL-C and LDL-C.
| Cas No : | 79902-63-9 |
|---|---|
| Name : | Simvastatin |
| Synonyms : | (1s-(1-alpha,3-dro-4-hydroxy-6-oxo-2h-pyran-2-yl)ethyl)-1-naphthalenyleste |
| Molecular Formula : | C25H38O5 |
| Melting Point : | 139°C |
| Boiling Point : | 564.9±50.0°C |
| Molecular Weight : | 418.57 |
| Density : | 1.11±0.1 G/cm3 |
| Solubility : | DMSO: ≥20mg/mL |
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