R-Mandelic Acid

R-Mandelic Acid API

MA is a large-molecule alpha-hydroxy acid with slow epidermal penetration. Similar to the other alpha-hydroxy acids described, MA decreases corneocyte adhesion and is keratolytic. Aside from acne treatment,MA is often used for skin rejuvenation and lightening.

R-Mandelic Acid API

Cas No :

611-71-2

Name :

R-Mandelic Acid

Synonyms :

(2R)-2-hydroxy-2-phenylacetic acid

Molecular Formula :

C8H8O3

Melting Point :

119 °C

Boiling Point :

321.8 °C

Molecular Weight :

152.15 g/mol

Density :

1.30 g/cm3

Solubility :

N/A

Uses :


  • R-Mandelic acid, a chiral resolving agent, is also used as a building block to synthesize pharmaceutical drugs such as penicillin and cephalosporin. It can be synthesized from (R,S)-mandelonitrile with high yield and enantioselectivity using nitrilase enzyme.