The inhibitory action of omeprazole was found to depend on acid induced transformation of omeprazole into an active inhibitor of the gastric H+K+ATPase, as no inhibition was obtained when omeprazole was incubated under neutral conditions with either the isolated gastric mucosal or the H+K+ATPase preparations.
Cas No : | 73590-58-6 |
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Name : | Omeprazole |
Synonyms : | 5-Methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-benzimidazole |
Molecular Formula : | C17H19N3O3S |
Melting Point : | 156 °C |
Boiling Point : | 600 °C at 760 mmHg |
Molecular Weight : | 345.4 g/mol |
Density : | 1.4±0.1 g/cm3 |
Solubility : | Soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF). |
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