Gemcitabine has self-potentiating pharmacological actions that can increase the probability of successful incorporation of gemcitabine triphosphate into the DNA chain: dFdCDP inhibits ribonucleotide reductase, an enzyme responsible for catalyzing the reactions that generate dCTP for DNA synthesis.
| Cas No : | 95058-81-4 |
|---|---|
| Name : | Gemcitabine |
| Synonyms : | 4-Amino-1-(2-deoxy-2,2-difluoro-β-D-erythro-pentofuranosyl)pyrimidin-2(1H)-on |
| Molecular Formula : | C9H11F2N3O4 |
| Melting Point : | >235°C |
| Boiling Point : | 482.7 °C |
| Molecular Weight : | 263.198 g/mol |
| Density : | 1.8±0.1 g/cm3 |
| Solubility : | Gemcitabine is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide, which should be purged with an inert gas. The solubility of gemcitabine in these solvents is approximately 0.25, 5, and 0.1 mg/ml, respectively. |
Advancing global health through high-quality APIs, intermediates, and surgical products. Trusted solutions driven by innovation, quality, and care.
Copyright © 2025 Healnith Pharmaceuticals All rights reserved.