Bromhexine acts on the mucus at the formative stages in the glands, within the mucus-secreting cells. Bromhexine disrupts the structure of acid mucopolysaccharide fibres in mucoid sputum and produces a less viscous mucus, which is easier to expectorate.
Cas No : | 3572-43-8 |
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Name : | Bromhexine |
Synonyms : | 2,4-Dibromo-6-{[cyclohexyl(methyl)amino]methyl}aniline |
Molecular Formula : | C14H20Br2N2 |
Melting Point : | 240-244°C |
Boiling Point : | 413.8±40.0 °C at 760 mmHg |
Molecular Weight : | 376.136 g·mol−1 |
Density : | 1.6±0.1 g/cm3 |
Solubility : | In aqueous systems bromhexine hydrochloride (Br-HCl) has a poor solubility (4.54 mg/g) and displays no amphiphilic character e.g. self association. Therefore the drug is molecularly dispersed in water until the solubility product of Br-HCl is exceeded |
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