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Atorvastatin

Atorvastatin API

Atorvastatin competitively inhibits 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. [2] By preventing the conversion of HMG-CoA to mevalonate, statin medications decrease cholesterol production in the liver.

Atorvastatin API

Cas No :

134523-00-5
Name :

Atorvastatin
Synonyms :

(3R,5R)-7-[2-(4-Fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid
Molecular Formula :

C33H35FN2O5
Melting Point :

164-180°C
Boiling Point :

722.2±60.0 °C at 760 mmHg
Molecular Weight :

558.64 g/mol
Density :

1.2±0.1 g/cm3
Solubility :

Insoluble in aqueous solutions of pH 4 and below.Very slightly soluble in distilled water, pH 7.4 phosphate buffer, and acetonitrile, slightly soluble in ethanol, and freely soluble in methanol.

Uses :


  • Atorvastatin is used together with a proper diet to lower cholesterol and triglyceride (fats) levels in the blood. This medicine may help prevent medical problems (eg, chest pain, heart attack, or stroke) that are caused by fats clogging the blood vessels.

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